smart 2000 video tracking system  (San Diego Instruments)

Journal: Redox Report : Communications in Free Radical Research

Article Title: EGCG-loaded nanoparticles attenuate post-SAH white matter injury by targeting HO-1/S100A10 to suppress oxidative stress-induced reactive astrocytes

doi: 10.1080/13510002.2026.2664955

Figure Lengend Snippet: Neuroprotective function of EGCG-NPs after SAH. (a) Representative swimming paths of mice in each group in the Morris water maze test after SAH, tracked and recorded by the SMART-2000 Video Tracking System. (b) Swimming speed of mice in each group measured over 200-s intervals, quantified and analysed by the SMART-2000 Video Tracking System based on the recorded swimming paths. (c) Distance travelled by mice in each group over time, dynamically tracked and quantified using the SMART-2000 Video Tracking System. (d) Fraction of time spent stationary by mice in each group, calculated and analysed by the SMART-2000 Video Tracking System. (e) Modified Garcia scores of mice after EGCG-NPs pretreatment and intracerebroventricular siHO-1 injection, evaluated by an investigator blinded to the experimental groups to ensure unbiased results. Lines and error bars represent the cohort mean ± SD from three independent experiments. Data was analysed using the Kruskal-Wallis non-parametric test followed by Duncan’s method for multiple comparisons (b-e). Significance: * p < 0.05 vs. Sham, ** p < 0.01 vs. Sham; # p < 0.05 vs. SAH, ## p < 0.01 vs. SAH.

Article Snippet: A video recording system was used to track the animals’ activities, and their swimming patterns were recorded and analysed using the SMART-2000 Video Tracking System (San Diego Instruments Inc., San Diego, CA, U.S.A.).

Techniques: Modification, Injection

Journal: Redox Report : Communications in Free Radical Research

Article Title: EGCG-loaded nanoparticles attenuate post-SAH white matter injury by targeting HO-1/S100A10 to suppress oxidative stress-induced reactive astrocytes

doi: 10.1080/13510002.2026.2664955

Figure Lengend Snippet: S100A10-mediated neurological deficits after SAH. (a, b) Immunofluorescence staining of MBP (green) in the ipsilateral corpus callosum after intracerebroventricular siS100A10 injection (a), with quantitative analysis of MBP fluorescence intensity performed using image analysis software (b). Nuclei were counterstained with DAPI (blue) to visualise cell nuclei. Scale bars: 50 μm. (c) Representative swimming trajectories of mice in each group in the Morris water maze test after SAH, tracked and recorded by the SMART-2000 Video Tracking System. (d) Swimming speed of mice in each group measured over 200-s intervals, quantified and analysed by the SMART-2000 Video Tracking System based on the recorded swimming trajectories. (e) Distance travelled by mice in each group over time, dynamically tracked and quantified using the SMART-2000 Video Tracking System during the Morris water maze test. (f) Fraction of time spent stationary by mice in each group, calculated and analysed by the SMART-2000 Video Tracking System. (g) Modified Garcia scores of mice after intracerebroventricular siS100A10 pretreatment, evaluated by an investigator blinded to the experimental groups to ensure unbiased results. Lines and error bars represent the cohort mean ± SD from three independent experiments. Statistical analysis: Data were analysed using the Kruskal-Wallis non-parametric test followed by Duncan’s method for multiple comparisons (d-g). # p < 0.05 vs. SAH, ## p < 0.01 vs. SAH.

Article Snippet: A video recording system was used to track the animals’ activities, and their swimming patterns were recorded and analysed using the SMART-2000 Video Tracking System (San Diego Instruments Inc., San Diego, CA, U.S.A.).

Techniques: Immunofluorescence, Staining, Injection, Fluorescence, Software, Modification